• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Friday, July 11, 2025
  • Login
Pioneer News
ADVERTISEMENT
  • Home
  • India
    • National
    • State News
  • Education
  • Business
  • World
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Travel
    • Fashion & Beauty
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Finance/Money
    • Agriculture
    • Science
    • Astrology
    • Social Work
    • Press Release
No Result
View All Result
  • Home
  • India
    • National
    • State News
  • Education
  • Business
  • World
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Travel
    • Fashion & Beauty
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Finance/Money
    • Agriculture
    • Science
    • Astrology
    • Social Work
    • Press Release
No Result
View All Result
Pioneer News
No Result
View All Result
Home Science

Novel technique may help in early detection of Cancer, Alzheimer’s, and Parkinson’s

Pioneer News by Pioneer News
February 24, 2021
in Science, Tech
0

New Delhi: Scientists from Raman Research Institute (RRI) have developed a new technique to measure DNA modifications that can have applications in the early diagnosis of multiple diseases like Cancer, Alzheimer’s, and Parkinson’s diseases.

DNA conformation, in particular, it’s supercoiling, plays an important structural and functional role in gene accessibility as well as in DNA condensation. Alteration in DNA affects their expression and functions. DNA controls cell survival through the genetic code as well as via modifications to its structure. The scientific community was looking for a technique with very high resolution to measure such modifications of DNA structures and observe and understand the molecular mechanisms associated with it to track rare diseases.

RelatedPosts

Global Innovator Radhakrishnan Arikrishna Perumal Sets a New Benchmark in Ethical AI and Insurance Technology

Global Innovator Radhakrishnan Arikrishna Perumal Sets a New Benchmark in Ethical AI and Insurance Technology

June 27, 2025
Kingston Reinforces Legacy of Performance with Refreshed XS Series External SSD Lineup

Kingston Reinforces Legacy of Performance with Refreshed XS Series External SSD Lineup

June 26, 2025

The novel nanopore-based platform developed by the scientists can directly measure such modifications or branched DNA properties with the single-molecule resolution even with extremely low amounts of sample. The platform and associated analysis techniques developed by the team can quantitatively assess the distribution of supercoiled branches on DNA plasmids (DNA molecule outside the chromosome).

ADVERTISEMENT

“Further optimization of the technique can help in the development of portable nano-bio sensors for detection and quantification of protein aggregates and cell-free DNA or nucleosomes. This may help in the early diagnosis of many diseases like Cancer, Alzheimer’s, and Parkinson’s diseases” said Prof GautamVivekSoni, the lead researcher. Currently, researchers at RRI are also exploring applications of this method for virus detection.

The measurement principle of the novel platform is analogous to the Archimedes principle. Individual analyte molecules are driven through a nanopore under an applied voltage, which, during translocation, results in a tiny electrical blip. Charges excluded by the analyte (supercoiled DNA) in the  nanopore are directly proportional to the volume of the particle and are directly measured as the current change. This method utilizes extremely low amounts of sample and can measure DNA structural changes ranging to a few nanometers resolution in the axis perpendicular to the translocation and few tens of nanometers along the translocation axis.

The research team comprise  Dr Sumanth Kumar Maheshwaram, Dr Koushik Sreenivasaa and Prof Gautam Vivek Soni. The research findings have been recently published in the journal ‘Nanoscale’. (India Science Wire)

Tags: DNA Modificationnanoporenew techniqueRRI
ShareTweetSharePinSendShareShareSend
ADVERTISEMENT
Pioneer News

Pioneer News

Related Posts

Global Innovator Radhakrishnan Arikrishna Perumal Sets a New Benchmark in Ethical AI and Insurance Technology
Tech

Global Innovator Radhakrishnan Arikrishna Perumal Sets a New Benchmark in Ethical AI and Insurance Technology

by Pioneer News
June 27, 2025
Kingston Reinforces Legacy of Performance with Refreshed XS Series External SSD Lineup
Tech

Kingston Reinforces Legacy of Performance with Refreshed XS Series External SSD Lineup

by Pioneer News
June 26, 2025
TCL Q6 Series: The Real Deal for Tech-Savvy TV Buyers This Year? (Yeah, We’re Looking Closely!)
Tech

TCL Q6 Series: The Real Deal for Tech-Savvy TV Buyers This Year? (Yeah, We’re Looking Closely!)

by Pioneer News
May 30, 2025
Synersoft Technologies Achieves ISO 27001 Certification Using Its Homegrown BLACKbox Cybersecurity Solution
Tech

Synersoft Technologies Achieves ISO 27001 Certification Using Its Homegrown BLACKbox Cybersecurity Solution

by Pioneer News
May 29, 2025
TCL Takes the Crown? 5 Reasons Why TCL’s Premium QD Mini LED Google TV Might Be the Best Smart TV Under ₹1 Lakh!
Tech

TCL Takes the Crown? 5 Reasons Why TCL’s Premium QD Mini LED Google TV Might Be the Best Smart TV Under ₹1 Lakh!

by Pioneer News
May 24, 2025
Next Post

Union Minister Dr Jitendra Singh lays the Foundation Stone of new Students' Hostels in the premises of the famous Cotton University

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

  • Trending
  • Comments
  • Latest
Things to Learn from The Weekly with ChoubeyJi

Things to Learn from The Weekly with ChoubeyJi

February 25, 2022
Oral Asformas – The Digital Marketing Entrepreneur who lit up his life through his Never-Back-Down attitude

Oral Asformas – The Digital Marketing Entrepreneur who lit up his life through his Never-Back-Down attitude

April 21, 2022
KGF Star Yash in Conversation with Anchor Anupam Anand

KGF Star Yash in Conversation with Anchor Anupam Anand

March 1, 2022
Choubey Ji is back with Season 2

Choubey Ji is back with Season 2

December 30, 2022

Changa Video sharing app crosses 2 million on play store

0

World’s first DeepUV Air Sanitizer, launched by Indian startup Dokat Inc.

0

Japan’s tech start-ups bitgrit and Atrae rolls out professional ‘matching’ app in India offering jobs in India

0

Surat’s company invents – low-cost,high-end ventilator in support of the Aatmanirbhar Bharat Abhiyan

0
Shaligram Infotech, A Trusted Microsoft Partner In India, Marks 10 Years With Rebranding And Expanded Global Focus

Shaligram Infotech, A Trusted Microsoft Partner In India, Marks 10 Years With Rebranding And Expanded Global Focus

July 9, 2025
Mumbai Metropolitan Region to Get Its First Space Education Lab in Thane!

Mumbai Metropolitan Region to Get Its First Space Education Lab in Thane!

July 7, 2025
VRA Health Bridges Healthcare Gaps: From COVID Crisis to Global Telemedicine Success

VRA Health Bridges Healthcare Gaps: From COVID Crisis to Global Telemedicine Success

July 7, 2025
Aayoma Home Appliances Pvt. Ltd: Built in India, Trusted Worldwide

Aayoma Home Appliances Pvt. Ltd: Built in India, Trusted Worldwide

July 7, 2025

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • Uncategorized
  • World
ADVERTISEMENT

Pioneer News, digital news and story platform bring you the news, articles, stories, and opinions on the latest happenings worldwide covering various sectors like nation, politics, and governance, social sector, review, foreign affairs, defence and security, latest review, lifestyle, entertainment, sports, technology, auto sectors, education, business and start-ups updates, Agriculture, Science, finance, money, food, and culture, etc.

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • Uncategorized
  • World
July 2025
M T W T F S S
 123456
78910111213
14151617181920
21222324252627
28293031  
« Jun    

Recent News

  • Shaligram Infotech, A Trusted Microsoft Partner In India, Marks 10 Years With Rebranding And Expanded Global Focus
  • Mumbai Metropolitan Region to Get Its First Space Education Lab in Thane!
  • VRA Health Bridges Healthcare Gaps: From COVID Crisis to Global Telemedicine Success
  • Aayoma Home Appliances Pvt. Ltd: Built in India, Trusted Worldwide
  • Luxiora Wins Emerging Beauty Brand Award at International Glory Awards 2025
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2021 Pioneer News.

No Result
View All Result
  • Home
  • India
    • National
    • State News
  • Education
  • Business
  • World
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Travel
    • Fashion & Beauty
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Finance/Money
    • Agriculture
    • Science
    • Astrology
    • Social Work
    • Press Release

© 2021 Pioneer News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In